Why do some girls not have dysmenorrhea? Uncover the scientific reasons behind
Dysmenorrhea is a common problem for many women every month, but some women experience almost no pain at all. What scientific reasons lie behind this difference? This article will analyze it from multiple perspectives such as physiology, genetics, and lifestyle, and attaches hot topic data from the entire Internet in the past 10 days for reference.
1. Physiological mechanisms of differences in dysmenorrhea

| Influencing factors | People with obvious dysmenorrhea | Those with mild menstrual cramps |
|---|---|---|
| prostaglandin levels | higher secretion | Secretion volume is low |
| Uterine position | Most posterior uterus | Anterior/median uterus |
| Cervical size | relatively narrow | relatively loose |
| endometrial thickness | thicker | thinner |
2. Genetic and physical factors
Research has found that if a mother's dysmenorrhea symptoms are mild, there is a 67% chance that her daughter will also have mild symptoms. This is directly related to the gene-regulated prostaglandin synthase activity.
| genetic factors | degree of influence |
|---|---|
| COMT gene variation | Pain sensitivity reduced by 23% |
| ESR1 gene polymorphisms | Differences in Estrogen Metabolism Efficiency |
| PTGS2 expression level | key to prostaglandin production |
3. Hot topics related to the entire network in the past 10 days
| topic | heat index | Platform |
|---|---|---|
| #Dysmenorrhea vaccine development progress | 82,000 | |
| #Dysmenorrhea-free physique development | 56,000 | little red book |
| #endometriosisscreening | 49,000 | Zhihu |
| #MenstrualExerciseControversy | 38,000 | Douyin |
4. Influence of lifestyle
Women who maintain regular exercise for a long time have a 42% lower incidence of dysmenorrhea than sedentary people. Key factors include:
5. Empirical data on dietary regulation
| Nutrients | The rate of dysmenorrhea in those with adequate intake | dysmenorrhea rate in deficient patients |
|---|---|---|
| Omega-3 | 31% | 58% |
| Magnesium | 27% | 63% |
| Vitamin B1 | 35% | 71% |
6. The regulating effect of psychological factors
Women who have been in a state of stress for a long time have 2.3 times the intensity of menstrual cramps as those who have a calm mind. There is a bidirectional regulatory pathway between the limbic system of the brain and the uterine plexus, and anxiety can aggravate smooth muscle spasm.
7. Differences in Medical Interventions
About 15% of women without dysmenorrhea have a natural luteal corpus function advantage, and their progesterone levels can be 18-22% higher than ordinary people. This hormone can effectively inhibit excessive uterine contraction.
From the above analysis, it can be seen that the difference in dysmenorrhea is the result of the joint action of multiple factors. Understanding these mechanisms can not only help women better manage menstrual health, but also provide directions for related medical research. The latest hot spots show that gene editing technology and targeted drug development are becoming new breakthroughs in solving the problem of dysmenorrhea.
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